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Thrombomodulin pAb

Cat no: BS5650

Thrombomodulin pAb

Thrombomodulin (TM), also called CD141, is a type I membrane receptor that is specific to endothelial cells. TM has a cysteine-rich extracellular domain with six EGF-like regions. It forms a complex with Thrombin, which activates Protein C to generate activated Protein C (APC), an anticoagulant enzyme. APC together with Protein S inhibits coagulation by inactivating Factors Va and VIIIa. Deletion of the TM gene results in embryonic lethality in mice.

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SPECIFICATIONS

Catalog Number

BS5650

Size

100ug/100ul

Applications

WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

liquid

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Synthetic peptide, corresponding to amino acids 530-575 of Human Thrombomodulin.

Species

Thrombomodulin pAb detects endogenous levels of Thrombomodulin protein.

Dilutions

WB: 1:500~1:1000\r

Swiss Prot

P07204

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul

Storage Buffer

1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Additional Info

For research use only, not for use in diagnostic procedure.

Molecular Weight

~ 60, 105 kDa

Alternative Names

TM; Fetomodulin; CD141; THBD; THRM

SUPPLIER INFO

Bioworld Technology, Inc.

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