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TIMP-4 (S206) pAb

TIMP-4 (S206) pAb

Cat no: BS1477

Supplier: Bioworld Technology, Inc.
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TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (for tissue inhibitor of metallopro teinases-1, -2, -3 and -4) complex with metalloproteinases such as collagenases, gelatinases and stromelysins, resulting in irreversible inactivation of the metalloproteinase. TIMP-1 was found to be identical to EPA (erythroidpotentiation activity). Parathyroid hormone has been shown to be a regulator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart and low levels of TIMP-4 are expressed in liver, brain, lung, thymus and spleen.
Catalogue number: BS1477
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: Q99727
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 172-220 of Human TIMP-4.
Species: TIMP4 (S206) pAb detects endogenous levels of TIMP4 protein.
Molecular weight: ~ 26 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: TIMP4; Tissue inhibitor of metalloproteinases 4; TIMP-4; TIMP4; 7079; TIMP4; 601915; Q99727;
Additional info: For research use only, not for use in diagnostic procedure.

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