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TIP60 (G82) pAb

TIP60 (G82) pAb

Cat no: BS1772

Supplier: Bioworld Technology, Inc.
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The MOZ gene was initially isolated as a consequence of two variant translocations that were identified in a distinct subtype of acute myeloid leukemias and resulted in the formation of MOZ fusion proteins. These fusions involve the HAT domain of MOZ with the activation domain of either transcriptional co-activator protein TIF2/GRIP1 or CBP, and lead to enhanced transcriptional activation by a mechanism involving aberrant histone acetylation. Additional MOZ-related proteins, including MORF (MOZrelated factor) and TIP60 (TAT-interacting proteins 60), share significant similarities with MOZ including the putuative HAT domain. TIP60 was originally identified as a co-activator for the HIV TAT protein and also functions as a nuclear hormone receptor co-activator that enhances ligand dependent steroid receptor-mediated transactivation involving the androgen, estrogen and progesterone receptors.
Catalogue number: BS1772
Reactivities: Human, Mouse
Hosts: Rabbit
Applications: Immunofluorescence, Immunohistochemistry
Size: 100ug/100ul
Swiss prot: Q92993
Dilutions: IHC: 1:50~1:200 IF: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 50-98 of Human TIP60.
Species: TIP60 (G82) pAb detects endogenous levels of TIP60 protein
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Tip60; HIV-1 Tat interactive protein; cPLA(2)-interacting protein; HTATIP; TIP60; TIP; ESA1; PLIP; cPLA2; HTATIP1; KAT5
Additional info: For research use only, not for use in diagnostic procedure.

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