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TIS11D (H243) Peptide

Cat no: BS2278P

TIS11D (H243) Peptide

TIS11D, also known as ZFP36LA (zinc finger protein 36, C3H type-like 2), BRF2 (butyrate response factor 2), ERF2 or RNF162C, is a 494 amino acid protein that localizes to the nucleus and contains two CSH1-type zinc fingers. Belonging to the TIS11 family of early response proteins, TIS11D is thought to function as a nuclear transcription factor that binds to 5'UUAUUUAUUU-3' core RNA sequences and may regulate growth factor-induced cellular responses. The gene encoding TIS11D maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes.

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SPECIFICATIONS

Catalog Number

BS2278P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide TIS11D (H243). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P47974

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS2278 TIS11D (H243) pAb.

Alternative Names

BRF2; Butyrate response factor 2; EGF response factor 2; ERF 2; ERF2; Protein TIS11D; RNF162C; ZFP36L2;

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