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TK (P7) Peptide

TK (P7) Peptide

Cat no: BS1601P


Supplier: Bioworld Technology, Inc.
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Thymidine kinase 2 (TK2) salvages mitochondrial (mt) pyrimidine deoxynucleosides for mtDNA precursor synthesis. TK2 phosphorylates these nucleosides to their corresponding nucleoside monophosphates using a nucleotide triphosphate as a donor. Deficiency of mitochondrial TK2 manifests as severe skeletal myopathy during infancy, due to depletion of mtDNA. Mutant enzyme possesses similar K(m) values to wild type, however, the V(max) is markedly decreased, leading to the decreased enzyme efficiency, which causes the disease.
Catalogue number: BS1601P
Applications: Block/Neutralize/Inhibit
Swiss prot: P04183
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide TK (P7). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: TK1; EC 2.7.1.21; TK2
Additional info: This peptide can be used with studies using BS1601 TK (P7) pAb.

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