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TLR7 (Toll Like Receptor 7, TLR-7, PRO285, UNQ248) (PerCP)

Cat no: T8050-71N

TLR7 (Toll Like Receptor 7, TLR-7, PRO285, UNQ248) (PerCP)

Toll-like receptor 7 (TLR7) is a 120kD (predicted, unglycosylated) type I transmembrane glycoprotein and member of the Toll-like receptor family. Human TLR7 is synthesized as a 1049aa precursor that contains a 26aa signal sequence, an 803aa extracellular domain (ECD), a 21aa transmembrane sequence, and a 189aa cytoplasmic domain. Mature human TLR7 is 81% aa identical to mature mouse TLR7. TLR7 is detected in brain, placenta, spleen, stomach, small intestine, lung, and in plasmacytoid pre-dendritic cells. Functionally, TLR7 participates in the innate immune response to microbial agents.\n\nApplications: \nSuitable for use in Flow Cytometry. Other applications not tested.\n\nRecommended Dilution:\nFlow Cytometry: 0.5ul labels 5 x 10e5 cells\nOptimal dilutions to be determined by the researcher.\n\nHybridoma: \nMouse myeloma cells with B cells from a mouse immunized with purified, E. coli-derived, recombinant human toll-like receptor 7 (aa360-516).\n\nStorage and Stability:\nMay be stored at 4 degrees C before opening. DO NOT FREEZE! Stable at 4 degrees C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months at 4 degrees C. Freezing PerCP conjugates will result in a substantial loss of activity. PerCP conjugates are sensitive to light.

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SPECIFICATIONS

Catalog Number

T8050-71N

Size

100Tests

Applications

FC

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid in saline, 0.5% BSA, 0.1% sodium azide. Labeled with PerCP.

P Type

Mab

Purity

Purified by Protein G affinity chromatography.

Isotype

IgG2A

Additional Info

Recognizes human TLR7.

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Applications

ELISA, FC, IHC, WB

Hosts

Mouse

More info

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA

Hosts

Mouse

Reactivities

Hum, Mouse

More info

Applications

ELISA

Hosts

Mouse

Reactivities

Hum, Mouse

More info

Applications

ELISA

Hosts

Mouse

More info
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