Home  >  Products  >  TMPRSS4 (Transmembrane Protease Serine 4, Channel-activating Protease 2, CAPH2, Membrane-type Serine Protease 2, MT-SP2, TMPRSS3, UNQ776/PRO1570)
TMPRSS4 (Transmembrane Protease Serine 4, Channel-activating Protease 2, CAPH2, Membrane-type Serine Protease 2, MT-SP2, TMPRSS3, UNQ776/PRO1570)

TMPRSS4 (Transmembrane Protease Serine 4, Channel-activating Protease 2, CAPH2, Membrane-type Serine Protease 2, MT-SP2, TMPRSS3, UNQ776/PRO1570)

Cat no: T8264-46C

Supplier: United States Biological
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This gene encodes a member of the serine protease family. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified as a gene overexpressed in pancreatic carcinoma. The encoded protein is membrane bound with a N-terminal anchor sequence and a glycosylated extracellular region containing the serine protease domain. Multiple transcript variants encoding different isoforms have been found for this gene. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:1000 Western Blot: 1-3ug/ml, observed in human bone marrow lysates on ~48kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: T8264-46C
Reactivities: Human, Mouse
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
References: 1. Dawelbait G, Winter C, Zhang Y, Pilarsky C, Grutzmann R, Heinrich JC, Schroeder M. Structural templates predict novel protein interactions and targets from pancreas tumour gene expression data. Bioinformatics. 2007 Jul 1;23(13):i115-24.
Additional info: Recognizes human TMPRSS4. Species sequence homology: Mouse.

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