TNF-alpha (Q178) Peptide

Cat no: BS1857P

Supplier: Bioworld Technology, Inc.

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Tumor Necrosis Factor Alpha (TNF alpha) is a protein secreted by lipopolysaccharide stimulated macrophages, and causes tumor necrosis when injected into tumour bearing mice. TNF alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia. TNF alpha exists as a multimer of two, three, or five noncovalently linked units, but shows a single 17 a band following SDS PAGE under non reducing conditions. TNF alpha is closely related to the 25 a protein Tumour Necrosis Factor beta (lymphotoxin), sharing the same receptors and cellular actions. TNF alpha causes cytolysis or cytostasis of certain transformed cells, being synergistic with interferon gamma in its cytotoxicity. Although it has little effect on many cultured normal human cells, TNF alpha appears to be directly toxic to vascular endothelial cells.

Catalogue number:	BS1857P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P01375
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide TNF-alpha (Q178). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Tumor necrosis factor; Cachectin; TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-a; Tumor necrosis factor, soluble form; TNF; TNFA; TNFSF2; TNFalpha; TNF alpha
Additional info:	This peptide can be used with studies using BS1857 TNF-alpha (Q178) pAb.

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TNF-alpha (Q178) Peptide

Cat no: BS1857P

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