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TNF-R1 (A405) Peptide

TNF-R1 (A405) Peptide

Cat no: BS1478P

Supplier: Bioworld Technology, Inc.
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Tumor Necrosis Factor (TNF) is a cytokine whose function is mediated through two distinct cell surface receptors (TNF Receptor I and TNF Receptor II) that are included in the TNF Receptor superfamily along with FAS antigen and CD40. TNF Receptors I and II are 55 and 75 kDa members, respectively, of a family of cell surface molecules including nerve growth factor receptor, Fas/Apo1, CD30, OX40, and 41BB, which are characterized by cysteine rich motifs in the extracellular domain. While TNF Receptor I and TNF Receptor II share 28% sequence homology in the extracellular domains, their intracellular domains lack sequence homology, suggesting that they differ in their internal signal transduction pathways. TNF Receptor I contains an approximately 80 amino acid death domain near its carboxy terminus capable of transmitting an apoptotic signal through its interaction with TRADD (TNF Receptor I associated death domain protein), and subsequent interactions with FADD.
Catalogue number: BS1478P
Applications: Block/Neutralize/Inhibit
Swiss prot: P19438
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide TNF-R1 (A405). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: p60; TNF-R1; TNF-RI; TNFR-I; p55; CD120a antigen; TNF receptor I; 7132; TNFRSF1A; 142680; P19438; CD120a; FPF; MGC19588; TBP1; TNF-R; TNF-R-I; TNF-R55; TNFAR; TNFR1; TNFR55; TNFR60; p55; p55-R;
Additional info: This peptide can be used with studies using BS1478 TNF-R1 (A405) pAb.

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