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TNFAIP3 pAb

TNFAIP3 pAb

Cat no: BS5592

Supplier: Bioworld Technology, Inc.
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A20, also referred to as TNF-(alpha)-induced protein 3 (TNFAIP3), is cytokine-inducible protein that functions to inhibit apoptosis and activate NF-kB. It was first identified as a TNF-(alpha) inducible primary response gene in human umbilical vein endothelial cells, and encodes a 790-amino acid protein containing seven Cys2/Cys2-zinc finger motifs. Constitutive expression of A20 is observed in lymphoid tissues, but it is transiently expressed in a variety of cell types in response to inflammatory signals such as TNF-(alpha), IL-1, phorbol esters, and LPS. Expression of A20 can confer resistance to apoptosis and NF-kB activation triggered by these signals, probably through interference with TRAF (TNF receptor associated factor) family members, and interaction with the NF-kB inhibiting protein ABIN.
Catalogue number: BS5592
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunofluorescence, Western Blot
Size: 100ug/100ul
Swiss prot: P21580
Dilutions: WB: 1:500~1:1000 IF: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 365-410 of Human TNFAIP3.
Species: TNFAIP3 pAb detects endogenous levels of TNFAIP3 protein.
Molecular weight: ~ 90 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Tumor necrosis factor alpha-induced protein 3; TNF alpha-induced protein 3; OTU domain-containing protein 7C; Putative DNA-binding protein A20; Zinc finger protein A20; A20p50; A20p37; TNFAIP3; OTUD7C
Additional info: For research use only, not for use in diagnostic procedure.

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