TNFAIP3 Peptide

Cat no: BS5592P

Supplier: Bioworld Technology, Inc.

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Additional Information

A20, also referred to as TNF-alpha-induced protein 3 (TNFAIP3), is cytokine-inducible protein that functions to inhibit apoptosis and activate NF-kB. It was first identified as a TNF-alpha inducible primary response gene in human umbilical vein endothelial cells, and encodes a 790-amino acid protein containing seven Cys2/Cys2-zinc finger motifs. Constitutive expression of A20 is observed in lymphoid tissues, but it is transiently expressed in a variety of cell types in response to inflammatory signals such as TNF-alpha, IL-1, phorbol esters, and LPS. Expression of A20 can confer resistance to apoptosis and NF-kB activation triggered by these signals, probably through interference with TRAF (TNF receptor associated factor) family members, and interaction with the NF-kB inhibiting protein ABIN.

Catalogue number:	BS5592P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P21580
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide TNFAIP3. (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Tumor necrosis factor alpha-induced protein 3; TNF alpha-induced protein 3; OTU domain-containing protein 7C; Putative DNA-binding protein A20; Zinc finger protein A20; A20p50; A20p37; TNFAIP3; OTUD7C
Additional info:	This peptide can be used with studies using BS5592 TNFAIP3 pAb.

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TNFAIP3 Peptide

Cat no: BS5592P

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