TNFRSF14 pAb

Cat no: BS6775

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

HVEM (herpes virus entry mediator A), also known as TR2, ATAR, HVEA, LIGHTR or TNFRSF14 (tumor necrosis factor receptor superfamily, member 14), is a 283 amino acid single-pass type I membrane protein that is widely expressed, with highest expression in lung, spleen and thymus. A member of the TNF receptor superfamily, HVEM mediates the entry of herpes simplex virus (HSV) 1 and 2 into T lymphocytes by serving as an attachment site for the HSV envelope glycoprotein D (gD).HVEM acts as a receptor for two cellular ligands, secreted lymphotoxin and LIGHT. A member of the TNF superfamily produced by activated T-cell, LIGHT is suggested to induce apoptosis and suppress tumor formation. Consisting of three TNFR-Cys repeats, HVEM plays a critical role in HSV pathogenesis. HVEM is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.

Catalogue number:	BS6775
Reactivities:	Human
Hosts:	Rabbit
Applications:	Immunohistochemistry, Western Blot
Size:	100ug/100ul
Swiss prot:	Q92956
Dilutions:	WB: 1:500~1:2000 IHC: 1:50~1:200
Form:	liquid
Storage buffer:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration:	1ug/ul
Antigen:	Recombinant full length Human TNFRSF14.
Species:	TNFRSF14 pAb detects endogenous levels of TNFRSF14 protein.
Molecular weight:	~ 31 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp:	Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names:	HVEML; ATAR; CD258; CD270; CD40 like protein precursor; Herpes virus entry mediator A; Herpesvirus entry mediator A; Herpesvirus Entry Mediator; Herpesvirus entry mediator ligand; HVEA; HVEM; HVEM L; HVEML; LIGHT; LIGHTR; TNFRSF14; TNFSF 14; TNR14; TR2; Tumor necrosis factor receptor like gene2; Tumor Necrosis Factor Receptor Superfamily Member 14; Tumor necrosis factor receptor superfamily member 14 precursor; Tumor necrosis factor receptor-like 2;
Additional info:	For research use only, not for use in diagnostic procedure.

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TNFRSF14 pAb

Cat no: BS6775

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