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Topo IIIbeta-1 (Q84) Peptide

Topo IIIbeta-1 (Q84) Peptide

Cat no: BS1908P

Supplier: Bioworld Technology, Inc.
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DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA by transiently breaking and rejoining DNA strands. Although DNA topoisomerase I and DNA topoisomerase II relax both positive and negative supercoils, DNA topoisomerase III relaxes only negative supercoils. DNA topoisomerase III alpha exists as a long and a short isoform, which are produced by alternative splicing. DNA topoisomerase III alpha, which localizes to the nucleolus, is constitutively expressed and remains at high levels throughout the cell cycle in HL-60 cells. DNA topoisomerase III beta exists as three isoforms, namely beta1, beta2 and beta3, also produced by alternative splicing. DNA topoisomerase III beta1 is expressed in testes, heart and skeletal muscle, whereas beta2 is expressed in thymus, kidney and pancreas.
Catalogue number: BS1908P
Applications: Block/Neutralize/Inhibit
Swiss prot: O95985
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide Topo IIIbeta-1 (Q84). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: TOP3B; TOP3B1; DNA topoisomerase 3-beta-1
Additional info: This peptide can be used with studies using BS1908 Topo IIIbeta-1 (Q84) pAb.

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