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TPX2 (Q330) Peptide

TPX2 (Q330) Peptide

Cat no: BS3016P

Supplier: Bioworld Technology, Inc.
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TPX2 (targeting protein for Xklp2) is a microtubule-associated protein involved in targeting the motor protein Xklp2 to microtubules. Ran-GTP activates TPX2 for the chromatin-induced microbutule assembly during M phase. Aurora-A kinase associates with TPX2 at the spindle apparatus and may regulate TPX2 via phosphorylation during the spindle assembly. TPX2 appears to play a structural role in spindle formation. TPX2 activates Eg2 in a microtubuledependent manner by stimulating the phosphorylation and kinase activity of Eg2. TPX2 is inactivated by binding to importin alpha, a nuclear import factor. Finally, the suppression of TPX2 with RNA interference causes defects in microtubule organization during mitosis.
Catalogue number: BS3016P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q9ULW0
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide TPX2 (Q330). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: TPX2; C20ORF1; C20ORF2; DIL-2; DIL2; FLS353; GD:C20ORF1; HCA519; HCTP4; P100; REPP86
Additional info: This peptide can be used with studies using BS3016 TPX2 (Q330) pAb.

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