TRAF6 (H154) Peptide

Cat no: BS3684P

Supplier: Bioworld Technology, Inc.

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Tumor necrosis factor receptor-associated factor 6 (TRAF6) regulates adaptive immunity, innate immunity and bone metabolism. TRAF6 is a ubiquitin (Ub) ligase that mediates the activation of protein kinases, such as transforming growth factor beta-activated kinase (TAK1) and IkB kinase (IKK), by catalyzing the formation of a unique polyubiquitin chain linked through Lys 63 of Ub. TRAF6 is essential for activating NFkB signaling pathway in response to interleukin-1 and Toll-like receptor ligands. The coiled-coil domain of TRAF6 is essential for its auto-ubiquitination and activating NFkB signaling pathway. TRAF6 interacts with various protein kinases including IRAK1/IRAK, SRC and PKC?, which provides a link between distinct signaling pathways.

Catalogue number:	BS3684P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	Q9Y4K3
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide TRAF6 (H154). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	TNF receptor-associated factor 6; E3 ubiquitin-protein ligase TRAF6; Interleukin-1 signal transducer; RING finger protein 85; TRAF6; RNF85; TRAF 6; TRAF-6;
Additional info:	This peptide can be used with studies using BS3684 TRAF6 (H154) pAb.

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TRAF6 (H154) Peptide

Cat no: BS3684P

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