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Translin (E121) Peptide

Translin (E121) Peptide

Cat no: BS2314P

Supplier: Bioworld Technology, Inc.
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Translin, also designated testis brain RNA-binding protein (TB-RBP), is a single-stranded DNA- and RNA-binding protein that binds to the 3' UTR regions (Y and H elements) of stored mRNAs, which suppresses their in vitro translation. The human translin gene maps to chromosome 2q21.1 and encodes a 26 kDa protein that has been highly conserved throughout evolution. Translin forms a ring-shaped structure, which is responsible for DNA binding, and also contains a leucine zipper motif, which is thought to enable translin to form dimers. Translin exports specific mRNAs out of the nucleus, supported by its localization in both the nuclei and cytoplasm of neurons, and regulates their translation.
Catalogue number: BS2314P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q15631
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide Translin (E121). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Translin; EC=3.1.-.-; Component 3 of promoter of RISC; C3PO; TSN
Additional info: This peptide can be used with studies using BS2314 Translin (E121) pAb.

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