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TRAP100 (K834) Peptide

TRAP100 (K834) Peptide

Cat no: BS1889P

Supplier: Bioworld Technology, Inc.
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In mammalian cells, transcription is regulated in part by high molecular weight coactivating complexes that mediate signaling between transcriptional activators and initiation factors. These complexes include the thyroid hormone receptor-associated protein (TRAP) complex, which interacts with thyroid receptors (TR), vitamin D receptors and other steroid receptors to facilitate hormone induced transcriptional activation. The TRAP complex consists of numerous proteins ranging in size from 20 to 240 kDa, including TRAP95, TRAP100, TRAP150, TRAP220 and TRAP230, and they are characterized by the presence of a nuclear receptor recognition motif, which mediates the ligand-dependent binding of TRAP proteins to the nuclear receptors. TRAP220 and TRAP100 are widely expressed and most abundantly detected in skeletal muscle, heart and placenta. TRAP95, TRAP150 and TRAP230 facilitate TR-induced transcription by associating with an additional transcriptional coactivating complex SMCC (SRB and MED protein cofactor complex), which consists of various subunits that share homology with several components of the yeast transcriptional mediator complexes.
Catalogue number: BS1889P
Applications: Block/Neutralize/Inhibit
Swiss prot: O75448
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide TRAP100 (K834). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: MED24; ARC100; CRSP complex subunit 4; Mediator complex subunit 24; Trap100; hTRAP100; DRIP100; ARC100; CRSP4; DRIP100; KIAA0130; THRAP4; TRAP100
Additional info: This peptide can be used with studies using BS1889 TRAP100 (K834) pAb.

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