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Treacle (Q55) Peptide

Cat no: BS2047P

Treacle (Q55) Peptide

Treacle is a serine/alanine-rich 1,411 amino acid nuclear phosphoprotein that interacts with upstream binding factor (UBF) and affects transcription of the ribosomal DNA gene. Treacle is also involved in early embryonic development, particularly in the craniofacial complex, and may play a role in nucleolarcytoplasmic transport. The Treacle protein contains three domains with unique N- and C-termini and a large central repeat domain. Mutations in TCOF1, the gene that encodes for Treacle, cause Treacher Collins-Franceschetti syndrome (TCS), a disorder characterized by defects in craniofacial development. Symptoms of TCS include conductive hearing loss, hypoplasia of the mandible and maxilla, downward sloping palpebral fissures and cleft palate.

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SPECIFICATIONS

Catalog Number

BS2047P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide Treacle (Q55). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

Q13428

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS2047 Treacle (Q55) pAb.

Alternative Names

MFD1; TCOF 1; TCOF; TCOF1; Treacher Collins syndrome protein; Treacle; Treacle protein;

SUPPLIER INFO

Bioworld Technology, Inc.

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