TRH-R1 (W234) Peptide

Cat no: BS3241P

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

Thyrotrophin-releasing hormone (TRH) is a hypothalamic tripeptide that stimulates, via its receptor in the anterior pituitary gland, the release of thyrotrophin (TSH) and prolactin. The TRH receptors, TRH-R1 and TRH-R2, are G protein-coupled proteins containing seven transmembrane domains and other conserved regions. In rat, two isoforms exist, TRH-R (412) and TRH-R (387), that differ at their carboxy termini. TRH receptors are distributed throughout the central and peripheral nervous systems and are present in a variety of tissues. TRH-R2 displays 50% homology to TRH-R1 and is more restricted to the central nervous system than TRH-R1. Mutation in the TRH receptor gene is associated with isolated central hypothyroidism, a rare disorder characterized by insufficient TSH secretion resulting in low levels of thyroid hormones.

Catalogue number:	BS3241P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P34981
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide TRH-R1 (W234). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Thyrotropin-releasing hormone receptor; TRH-R; Thyroliberin receptor; TRHR
Additional info:	This peptide can be used with studies using BS3241 TRH-R1 (W234) pAb.

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TRH-R1 (W234) Peptide

Cat no: BS3241P

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