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Trypsin-3 (M166) Peptide

Cat no: BS3707P

Trypsin-3 (M166) Peptide

In the small intestine, each isoform is cleaved by Enterokinase into its active form, Trypsin-1, Trypsin-2 and Trypsin-3, respectively. All trypsins are members of the serine protease trypsin family. The activated trypsins go on to activate other protease zymogens and play a role in the autoactivation of trypsinogens. This suggests an important role for trypsins in digestion. Mutations in the gene encoding Trypsin-1 that stimulate its activity are associated with autosomal dominant hereditary pancreatitis (HCP), also known as chronic pancreatitis (CP), a disease characterized by persistent, severe abdominal pain due to calcifications of the parenchyma, pancreatic stones, cysts and pancreatic head enlargement. Trypsin-3 is expressed in the brain in addition to the pancreas.

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SPECIFICATIONS

Catalog Number

BS3707P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide Trypsin-3 (M166). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P35030

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS3707 Trypsin-3 (M166) pAb.

Alternative Names

Trypsin-3; Brain trypsinogen; Mesotrypsinogen; Serine protease 3; Serine protease 4; Trypsin III; Trypsin IV; PRSS4; TRY3; TRY4; PRSS3

SUPPLIER INFO

Bioworld Technology, Inc.

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