TSC22 (E73) Peptide

Cat no: BS2661P

Supplier: Bioworld Technology, Inc.

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Transforming growth factor-beta-stimulated clone-22 (TSC-22) acts as a transcriptionalregulator to modulate cell growth and differentiation and cell death. TSC-22 contains a leucine zipper domain as well as a nuclear export signal, resulting in cytoplasmic localization in living cells. However, concomitant with the induction of apoptosis, TSC-22 translocates from the cytoplasm to the nucleus and shows transcriptional regulatory activity. TSC-22 acts as a major downstream component in the TGF-beta pathway, and also the PPARgamma signalling pathway. The association of these two pathways with tumor suppression, and the significant downregulation of TSC-22 mRNA in various cancer types, such as brain and salivary gland tumors, imply an antiproliferative role for TSC-22.

Catalogue number:	BS2661P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	Q15714
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide TSC22 (E73). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	TSC22 domain family protein 1; Cerebral protein 2; Regulatory protein TSC-22; TGFB-stimulated clone 22 homolog; Transforming growth factor beta-1-induced transcript 4 protein; TSC22D1; KIAA1994; TGFB1I4; TSC22; hucep-2
Additional info:	This peptide can be used with studies using BS2661 TSC22 (E73) pAb.

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TSC22 (E73) Peptide

Cat no: BS2661P

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