TXA synthase (F456) Peptide

TXA synthase, also referred to as thromboxane synthase or CYP5, is an enzyme that catalyzes the conversion of the prostaglandin endoperoxide (PGH2) into Thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. TXA synthase is an important part of the cytochrome P450 system. Thromboxane A2 plays a pivotal role in the maintenance of hemostasis and cardiovascular diseases along with Prostacyclin. The expression of TXA synthase has been found to be consistently upregulated in several types of cancer tissues suggesting the involvement of this enzyme in tumor growth in humans. Thromboxanes are produced by TXA synthase in excess in inflammatory bowel disease.

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SPECIFICATIONS

Catalog Number

BS9278P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide TXA synthase (F456). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P24557

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS9278 TXA synthase (F456) pAb.

Alternative Names

BDPLT14; CYP5; CYP5A1; Cytochrome P450 5A1; Cytochrome P450; family 5; subfamily A; polypeptide 1; FLJ52771; GHOSAL; Platelet cytochrome P450 subfamily V; TBXAS1; THAS; THAS; Thromboxane A synthase 1 (platelet); Thromboxane A synthase 1 (platelet; cytochrome P450; family 5; subfamily A); Thromboxane A synthase 1; Thromboxane A synthase 1 platelet cytochrome P450 subfamily V; Thromboxane-A synthase; TS; TXA synthase; TXAS; TXS;