TYK2 (V1048) Peptide

Cat no: BS3713P

Supplier: Bioworld Technology, Inc.

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Tyk 2 belongs to the family of non-receptor janus tyrosine kinases, which regulate a spectrum of cellular functions occurring downstream of activated cytokine receptors in the lympho-hematopoietic system. Immunological stimuli, such as interferons and cytokines, recruit STAT transcription factors to the cytokine receptor where Tyk 2 is associated. Tyk 2 then phosphorylates proximal STAT factors, which subsequently dimerize, translocate to the nucleus, and bind to cis elements upstream of target gene promoters to regulating transcription. The canonical JAK-STAT pathway is integral to maintaining a normal immune system by stimulating proliferation, differentiation, survival, and host resistance to pathogens. Cytokine induced pro-inflammatory responses are attractive targets for anti-inflammatory therapies, specifically at the level of Jak-STAT signaling.

Catalogue number:	BS3713P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P29597
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide TYK2 (V1048). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	JTK 1; Protein Tyrosine Kinase 2; JTK 1; Protein Tyrosine Kinase 2; TYK 2; Tyrosine kinase 2; JTK1; Non receptor tyrosine protein kinase TYK2; Non receptor tyrosine protein kinase 2
Additional info:	This peptide can be used with studies using BS3713 TYK2 (V1048) pAb.

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TYK2 (V1048) Peptide

Cat no: BS3713P

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