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UBE4A pAb

Cat no: BS5971

UBE4A pAb

UBE4A (ubiquitin conjugation factor E4 A), also known as E4, UFD2 or UBOX2, is a 1,066 amino acid protein that functions in the multiubiquitin pathway of protein degradation. Expressed in cortical neurons and in tubular kidney cells, UBE4A is the human homolog of the Sacch-aromyces cerevisiae UFD2 protein and functions with the UBE (ubiquitin enzymes) proteins to catalyze ubiquitin chain assembly. UBE4A may be in-volved in cell growth and differentiation and can act as an autoantigen in scleroderma, a disease characterized by excessive deposits of collagen in the skin or other organs. Two isoforms of UBE4A exist due to alternative splicing events.

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SPECIFICATIONS

Catalog Number

BS5971

Size

100ug/100ul

Applications

WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

liquid

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Synthetic peptide, corresponding to amino acids 183-228 of Human UBE4A.

Species

UBE4A pAb detects endogenous levels of UBE4A protein.

Dilutions

WB: 1:500~1:1000\r

Swiss Prot

Q14139

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul

Storage Buffer

1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Additional Info

For research use only, not for use in diagnostic procedure.

Molecular Weight

~ 125 kDa

Alternative Names

Ubiquitin conjugation factor E4 A; KIAA0126

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