UCN (A103) Peptide

Cat no: BS1488P

Supplier: Bioworld Technology, Inc.

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Urocortins 1, 2 and 3 are the mammalian homologs of fish urotensin I. Mammalian urocortin is a member of the corticotropin-releasing hormone(CRH) family that is expressed in a region of the rat midbrain. The distinct expression pattern in discrete brain regions suggests that it influences such behavior as feeding, anxiety and auditory processing. Synthetic human urocortin binds with high affinity to CRH receptors and acts in vitro to release ACTH from dispersed rat anterior pituitary cells. It is suggested that urocortin may be an endogenous CRF-like factor in the brain responsible for the effects of stress on appetite. The gene which encodes urocortin maps to human chromosome 2. Specifically, urocortin III is a specific ligand for CRF type 2 receptor which mediates stress-coping responses. Human urocortin I and III are expressed in the human heart. Urocortin III is also expressed in the pituitary gland, adrenal gland, GI tract, ovary, spleen, brain and kidney.

Catalogue number:	BS1488P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P55089
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide UCN (A103). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	UCN; MGC129974; MGC129975; UI; UROC
Additional info:	This peptide can be used with studies using BS1488 UCN (A103) pAb.

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UCN (A103) Peptide

Cat no: BS1488P

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