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UGDH / UDP-GlcDH (L433) Peptide

UGDH / UDP-GlcDH (L433) Peptide

Cat no: BS3411P

Supplier: Bioworld Technology, Inc.
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UDP-GlcDH (also called P-glucose 6-dehydrogenase, UGDH or UDPGDH) is a member of the UDP-glucose/GDP-mannose dehydrogenase family. UDP-GlcDH converts UDP-glucose to UDP-glucuronic acid, which is a crucial component in the biosynthesis of the glycosaminoglycans, hyaluronan, heparan sulfate and chondroitin sulfate. Found as common components of the extracellular matrix, these glycosaminoglycans are significant in signal transduction, cell migration, cancer growth and cancer metastasis. UDP-glucuronic acid (UDP-GlcA) is needed in the liver for the excretion of toxic compounds. UDP-GlcDH is a ubiquitously expressed protein most abundant in the liver. The protein structure of UDP-GlcDH was first analyzed in cow liver and found to be a homohexamer. This structure is well conserved between species and phyla with an overall 97% sequence identity shared between different species of mammals. Research indicates that UDP-GlcDH expression is upregulated by TGFbeta and downregulated by hypoxia.
Catalogue number: BS3411P
Applications: Block/Neutralize/Inhibit
Swiss prot: O60701
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide UGDH / UDP-GlcDH (L433). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: GDH; UDP Glc dehydrogenase; UDP GlcDH; UDP glucose 6 dehydrogenase; UDP-Glc dehydrogenase; UDP-GlcDH; UDP-glucose 6-dehydrogenase; UDP-glucose dehydrogenase; UDPGDH; UGD; Ugdh; UGDH; Uridine diphospho glucose dehydrogenase;
Additional info: This peptide can be used with studies using BS3411 UGDH / UDP-GlcDH (L433) pAb.

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