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UHRF1 pAb (ChIP Grade)

UHRF1 pAb (ChIP Grade)

Cat no: BS7227


Supplier: Bioworld Technology, Inc.
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UHRF1, also named as ICBP90, NP95 and RNF106, is a putative E3 ubiquitin-protein ligase. It may participate in methylation-dependent transcriptional regulation. UHRF1 binds to inverted 5-CCAAT-3 box 2 in the TOP2A promoter, and activates TOP2A expression. It is important for G1/S transition and may be involved in DNA repair and chromosomal stability. UHRF1s ability to repress its direct target gene expression is dependent on PHD(UHRF1) binding to unmodified H3R2.
Catalogue number: BS7227
Reactivities: Human
Hosts: Rabbit
Applications: Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 100ug/100ul
Swiss prot: Q96T88
Dilutions: WB: 1:500~1:2000 IHC: 1:50~1:200 IF: 1:20~1:50 IP: 1:20~1:50 CHIP: 1:20~1:50
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Recombinant full length Human UHRF1.
Species: UHRF1 pAb detects endogenous levels of UHRF1 protein.
Molecular weight: ~ 90, 110 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: E3 ubiquitin-protein ligase UHRF1; Nuclear protein 95; Nuclear zinc finger protein Np95; HuNp95; hNp95; RING finger protein 106; Transcription factor ICBP90; hUHRF1; ICBP90; NP95; RNF106
Additional info: For research use only, not for use in diagnostic procedure.

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