Home  >  Products  >  VAMP 4 (Vesicle Associated Membrane Protein 4, Vesicle-associated Membrane Protein 4 Isoform CRA a, Vesicle-associated Membrane Protein 4 Isoform CRA b, VAMP4, VAMP-4 Protein, VAMP24)
VAMP 4 (Vesicle Associated Membrane Protein 4, Vesicle-associated Membrane Protein 4 Isoform CRA a, Vesicle-associated Membrane Protein 4 Isoform CRA b, VAMP4, VAMP-4 Protein, VAMP24)

VAMP 4 (Vesicle Associated Membrane Protein 4, Vesicle-associated Membrane Protein 4 Isoform CRA a, Vesicle-associated Membrane Protein 4 Isoform CRA b, VAMP4, VAMP-4 Protein, VAMP24)

Cat no: V2024-60A

Supplier: United States Biological
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The vesicle associated membrane proteins (VAMP) or synaptobrevins are calcium binding proteins specific to eukaryotes. VAMPs, along with synaptosomal associated protein of 25kD (SNAP 25) and syntaxin, form the core complex of soluble NSF attachment protein receptor (SNARE) proteins that interact with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and alpha-SNAP. These membrane associated proteins play a key role in the regulation of vesicle membrane fusion with the plasma membrane. The Clostridium tetani neurotoxin is a metalloprotease with specificity for VAMP. In Alzheimer?s disease, VAMP levels of all isoforms appear to be significantly lowered. Applications: Suitable for use in Immunofluorescence and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degrees C. Aliquots are stable for at least 3 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: V2024-60A
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunofluorescence, Western Blot
Size: 100ug
Form: PBS, 1 mg/ml BSA, 0.05% sodium azide
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: Kreykenbohm V et al. The SNAREs vti1a and vti1b have distinct localization and SNARE complex partners. Eur J Cell Biol 81:273-80 (2002).
Additional info: Species Crossreactivity: Crossreacts with Human, Rat and Mouse.

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