VAMP (Vesicle-Associated Membrane Protein, Synaptobrevin, SYB)

Applications: \nSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.\n\nRecommended Dilution:\nWestern Blot: 1:1000 \nImmunohistochemistry: paraffin\nOptimal dilutions to be determined by the researcher.\n\nPositive Control: \nImmunohistochemistry: Brain \n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

V2024C

Size

200ug

Applications

ELISA, IHC, WB

Hosts

Mouse

Reactivities

Hum, Prc

Form

Supplied as a liquid in PBS, 0.09% sodium azide.

P Type

Mab

Purity

Purified

Isotype

IgG1

References

1. Honer, W.G. et al. (1994) Hippocampal synaptic pathology in patients with temporal lobe \nepilepsy. Acta Neuropathol. 87: 202-210. 2. Honer, W.G. et al. (1992) Regional synaptic pathology in Alzheimer's disease. Neurobiol. Aging. 13: 375-382. 3. Honer, W.G. et al. (1993) Human synaptic proteins with a heterogeneous distribution in cerebellum and visual cortex. Brain Res. 609: 9-20. 4. Honer, W.G. et al. (1992) Characterization of a synaptic antigen of interest in neuropsychiatric \nillness. Biol. Psychiatry 31: 147-158. 5. Honer, W.G. et al. (1989) Monoclonal antibodies to study the brain in schizophrenia. Brain Res. 500: 379-383. 6. Masliah, E. et al. (1994) Topographical distribution of synaptic-associated proteins in the neuritic plaques of Alzheimer's disease hippocampus. Acta Neuropathol. 87: 135-142. 7. Simpson, I.A. et al. (1994) Decreased concentrations of GLUT1 and GLUT3 glucose transporters in the brains of patients with Alzheimer's disease. Ann. Neurol. 35: 546-551. 8. Wakabayashi, K. et al. (1994) Synapse alterations in the hippocampalentorhinal formation in Alzheimer's disease with and without Lewy body disease. Brain Res. 667: 24-32. 9. Dickson, D.W. et al. (1994) Hippocampal sclerosis: a common pathological feature of dementia in very old (>80 years of age) humans. Acta Neuropathologica 88: 212-221. 10. Dickson, D.W. et al. (1995) Correlations of synaptic markers with cognitive status in prospectively studied elderly humans. Neurobiol. Aging 16: 285-98.

Additional Info

Recognizes human Synaptobrevin. Species Crossreactivity: porcine. Non-reactive with rat.

Alternative Names

Cellubrevin, CEB, DKFZp686H12131, FLJ11460, Synaptobrevin-1, SYB1, Synaptobrevin-2, SYB2, Synaptobrevin-3, SYB3, Vesicle-associated Membrane Protein 1 (Synaptobrevin 1), VAMP1, VAMP-1, Vesicle-associated Membrane Protein 2 (Synaptobrevin 2), VAMP2, VAMP-2, Vesicle-associated Membrane Protein 3 (Cellubrevin), VAMP3, VAMP-3