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Vasoactive Intestinal Peptide (VIP)

Cat no: V2115-07

Vasoactive Intestinal Peptide (VIP)

Located in the nerve fibers in the central and peripheral nervous system, VIP is probably acting as a neurotransmitter. The Verner-Morrison or Water Diarrhea Hypokalemia and Achlorhydria (WDHA) syndrome is a characteristic clinical syndrome associated with overproduction of VIP from endocrine tumors. VIP-producing tumors are usually neuroblastomas or endocrine tumors in the pancreas. The localization of the antigen is extracellular and cytoplasmic.\n\nApplications:\nSuitable for use in Immunohistochemistry. Other applications not tested.\n\nRecommended Dilution: \nImmunohistochemistry (frozen sections, cell preparations, and paraffin sections): 1:50-1:100. No pretreatment required. Incubate for 1hr at RT.\nOptimal dilutions to be determined by the researcher.\n\nPositive Control:\nIleum\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

V2115-07

Size

250ul

Applications

IHC

Hosts

Rabbit

Reactivities

Hum, Rat, Fel, Prc

Form

Supplied as a liquid, 0.1% sodium azide.

P Type

Pab

Purity

Serum

Isotype

IgG

References

Karila P et al: Anally projecting neurons exhibiting immunoreactivity to galanin NOS and VIP, detected by confocal laserscanning microscope, in the intestine of the Atlantic cod, Gadus morhua. Cell & Tissue Res 287, 525-533 (1997).

Additional Info

Recognizes porcine Vasoactive Intestinal Peptide. Species Crossreactivity: Most mammals, human, feline, rat and fish.

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