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VaV1 (A168) Peptide

VaV1 (A168) Peptide

Cat no: BS1370P


Supplier: Bioworld Technology, Inc.
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The Vav gene was originally identified on the basis of its oncogenic activation during the course of gene transfer assays. The major translational product of the Vav proto-oncogene has been identified as a protein containing an array of structural motifs. Contained within its amino terminus are a helix-loop-helix domain and a leucine zipper motif similar to that of Myc family proteins; deletion of this region of p95Vav causes its oncogenic activation. In addition, p95Vav contains an SH2 domain, which could indicate its role as a substrate for tyrosine kinases. Expression of p95Vav is limited exclusively to cells of hematopoietic origin, including those of the erythroid, lymphoid and myeloid lineages.
Catalogue number: BS1370P
Applications: Block/Neutralize/Inhibit
Swiss prot: P15498
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide VaV1 (A168). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Proto-oncogene vav; VAV
Additional info: This peptide can be used with studies using BS1370 VaV1 (A168) pAb.

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