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Vinculin (L817) Peptide

Vinculin (L817) Peptide

Cat no: BS1700P

Supplier: Bioworld Technology, Inc.
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Focal adhesions are identified as areas within the plasma membrane of tissue culture cells that adhere tightly to the underlying substrate. In vivo, these regions are involved in the adhesion of cells to the extracellular matrix. Paxillin and vinculin are cytoskeletal, focal adhesion proteins that are components of a protein complex which links the Actin network to the plasma membrane. Vinculin binding sites have been identified on other cytoskeletal proteins, including Talin and alpha-actinin. In addition, vinculin, Talin and alpha-actinin each contain Actin binding sites. Expression of vinculin and Talin has been shown to be affected by the level of Actin expression. alpha-Actinin has been shown to link Actin to integrins in the plasma membrane through interactions with the vinculin and Talin complex or by a direct interaction with integrin.
Catalogue number: BS1700P
Applications: Block/Neutralize/Inhibit
Swiss prot: P18206
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide Vinculin (L817). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: VCL
Additional info: This peptide can be used with studies using BS1700 Vinculin (L817) pAb.

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