VPAC1 (V371) Peptide

Cat no: BS3211P

Supplier: Bioworld Technology, Inc.

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The vasoactive intestinal peptide (VIP) and the pituitary adenylate cylaseactivating polypeptide (PACAP) belong to a superfamily of peptide hormones that include glucagon, secretin and growth hormone releasing hormone. The effects of VIP and PACAP are mediated by three G-protein coupled receptors, VPAC1, VPAC2 and the PACAP receptor (also designated PAC1-R). The VPAC receptors have equal affinities for VIP and PACAP, which stimulate the activation of adenylyl cyclase. Both VPAC1, a 47 kDa protein, and VPAC2, a 65 kDa protein, are abundantly expressed in brain and T cells, where they modulate neuronal differentiation and T cell activation, respectively. The PACAP receptor is a seven transmembrane protein that produces at least eight isoforms by alternative splicing. Each isoform is associated with a specific signaling pathway and a specific expression pattern. The PACAP receptor, which is thought to play an integral role in brain development, preferentially binds PACAP in order to stimulate a cAMP-protein kinase A signaling pathway.

Catalogue number:	BS3211P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P32241
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide VPAC1 (V371). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	VIPR1; VIPR1; PACAP-R2; VIP-R-1; Vasoactive intestinal polypeptide receptor 1
Additional info:	This peptide can be used with studies using BS3211 VPAC1 (V371) pAb.

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VPAC1 (V371) Peptide

Cat no: BS3211P

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