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VPAC2 (F122) Peptide

VPAC2 (F122) Peptide

Cat no: BS3212P

Supplier: Bioworld Technology, Inc.
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The vasoactive intestinal peptide (VIP) and pituitary adenylate cylase-activating polypeptide (PACAP) belong to a superfamily of peptide hormones that include glucagon, secretin and growth hormone releasing hormone. The effects of VIP and PACAP are mediated by three G-protein coupled receptors, VPAC1, VPAC2 and the PACAP receptor (also designated PAC1-R). The VPAC receptors have equal affinities for VIP and PACAP, which stimulate the activation of adenylyl cyclase. Both VPAC1 and VPAC2 are abundantly expressed in brain and T cells, where they modulate neuronal differentiation and T cell activation, respectively. The PACAP receptor is a seven transmembrane protein that produces at least eight isoforms by alternative splicing. Each isoform is associated with a specific signaling pathway and a specific expression pattern. The PACAP receptor, which is thought to play an integral role in brain development, preferentially binds PACAP in order to stimulate a cAMP-protein kinase A signaling pathway.
Catalogue number: BS3212P
Applications: Block/Neutralize/Inhibit
Swiss prot: P41587
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide VPAC2 (F122). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Vasoactive intestinal polypeptide receptor 2VIP-R-2,Helodermin-preferring VIP receptor,Pituitary adenylate cyclase-activating polypeptide type III receptor,PACAP type III receptor,PACAP-R-3,PACAP-R3,VPAC2,VIP2R,VIPR2
Additional info: This peptide can be used with studies using BS3212 VPAC2 (F122) pAb.

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