WASP (E284) Peptide

Cat no: BS1607P

Supplier: Bioworld Technology, Inc.

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The Wiskott-Aldrich syndrome (WAS) is a disorder that results from a monogenic defect that has been mapped to the short arm of the X chromosome at Xp11.23. WAS is characterized by thrombocytopenia, eczema, defects in cell-mediated and humoral immunity and a propensity for lymphoproliferative disease. The gene that is mutated in the syndrome encodes a 53 kDa proline-rich protein of unknown function designated WAS protein (WASP). A clue to WASP function came from the observation that T cells from affected males had an irregular cellular morphology and a disarrayed cytoskeleton suggesting the involvement of WASP in cytoskeletal organization. Close examination of the WASP sequence revealed a putative Cdc42/Rac interacting domain, homologous with those found in PAK65 and ACK. Subsequent investigation has shown WASP to be a true downstream effector of Cdc42.

Catalogue number:	BS1607P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P42768
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide WASP (E284). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	IMD2; SCNX; THC; THC1; Thrombocytopenia 1 (X linked); U42471; Was; WASp; WASP; Wiskott Aldrich syndrome (eczema thrombocytopenia); Wiskott Aldrich syndrome protein; Wiskott-Aldrich syndrome protein;
Additional info:	This peptide can be used with studies using BS1607 WASP (E284) pAb.

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WASP (E284) Peptide

Cat no: BS1607P

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