WBSCR11 (K94) Peptide

Williams-Beuren syndrome (WBS) is a developmental disorder caused by the hemizygous microdeletion on chromosome 7q11.23. WBS is an autosomal dominant genetic condition that is characterized by physical, cognitive and behavioral traits. The physical traits associated with WBS include facial dysmorphology, vascular stenoses, growth deficiencies, dental anomalies and neurologic and musculoskeletal abnormalities. Mild retardation, a weakness in visual-spatial skills, anxiety and a short attention span are typical cognitive and behavioral traits of WBS patients. The WBSCR11 gene is located within the WBS deletion and may contribute to the developmental symptoms found in WBS because of a loss of the encoded transcription factor. WBSCR11 is also designated GRF2IRD1, GTF3, Cream1 and MusTRD1 in human and BEN in mouse, due to slight differences in gene structure. WBSCR11 is expressed in all adult tissues as several variants and has discrete spatial and temporal expression during embryogenesis.

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SPECIFICATIONS

Catalog Number

BS2161P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide WBSCR11 (K94). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

Q9UHL9

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS2161 WBSCR11 (K94) pAb.

Alternative Names

General transcription factor 3C polypeptide 3; TFIIIC102; Transcription factor IIIC 102 kDa subunit; TFIIIC-gamma; Transcription factor IIIC gamma subunit