Wnt-1 (G331) Peptide

Cat no: BS1777P

Supplier: Bioworld Technology, Inc.

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Products of the highly conserved Wnt gene family play key roles in regulating cellular growth and differentiation. The prototype member of the Wnt gene family, Wnt-1, is a cysteine-rich secreted glycoprotein that associates with cell membranes and likely functions as a key regulator of cellular adhesion. beta-catenin, a cadherin-binding cellular adhesion protein which also binds the tumor supressor gene APC, has been identified as a downstream target of a signal transduction pathway mediated by Wnt-1. Wnt-1 is essential for normal development of the embryonic nervous system and its expression is normally limited to the embryonic neural tube and adult spermatids. When improperly expressed in mammary tissue, Wnt-1 contributes to hyperplasia and tumorigenic progression. Wnt family members have been shown to interact with Sonic hedgehog (Shh) in vivo to induce myogenesis in somitic tissue.

Catalogue number:	BS1777P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P04628
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide Wnt-1 (G331). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Proto-oncogene Wnt-1; Proto-oncogene Int-1 homolog; WNT1; INT1; WNT 1
Additional info:	This peptide can be used with studies using BS1777 Wnt-1 (G331) pAb.

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Wnt-1 (G331) Peptide

Cat no: BS1777P

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