XIAP (G81) Peptide

The human X chromosome linked Inhibitor of Apoptosis Protein (XIAP) is a major member of the inhibitor of apoptosis (IAP) family. XIAP functions by direct binding and inhibition of several caspases, including Caspase 3, Caspase 7 and Caspase 9. During apoptosis XIAP is specifically cleaved by Caspase 3 and partially loses its function. In addition to blocking the apoptosis signaling pathway, XIAP can also bind several other proteins in the bone morphogenetic protein (BMP) signaling pathway and act as a coupler between the membrane BMP receptor and the TAB1 TAK1 complex by binding to these proteins.

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SPECIFICATIONS

Catalog Number

BS1609P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide XIAP (G81). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P98170

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS1609 XIAP (G81) pAb.

Alternative Names

XIAP; EC 6.3.2.-; E3 ubiquitin-protein ligase XIAP; Inhibitor of apoptosis protein 3; X-linked inhibitor of apoptosis protein; X-linked IAP; IAP-like protein; HILP; XIAP; API3. Apoptosis Inhibitor 3. Baculoviral IAP Repeat Contai