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Products XPG (Xeroderma Pigmentosum Type G, ERCC5, ERCM2, Excision Repair Cross Complementing Rodent Repair Deficiency, UVDR, Xeroderma Pigmentosum Complementation Group G, XPGC, DNA Repair Protein Complementing XP-G Cells, DNA Excision Repair Protein ERCC-5)
| Catalogue number: | X1048-01A |
| Hosts: | Mouse |
| Applications: | Immunohistochemistry, Immunoprecipitation, Western Blot |
| Size: | 100ug |
| Form: | Supplied as a liquid in PBS. No preservative added. |
| P type: | Mab |
| Isotype: | IgG2a |
| Purity: | Purified by Protein A affinity chromatography. |
| References: | 1. Evans, E. et al. (1997) Open complex formation around a lesion during nucleotide excision repair provides a structure for cleavage by human XPG protein. EMBO J. 16:625-38. 2. O'Donovan, A. et al. (1994) Isolation of active recombinant XPG protein, a human DNA repair endonuclease. J Biol Chem. 269:15965-8. 3. Nouspikel, T. et al. (1997) A common mutational pattern in Cockayne syndrome patients from xeroderma pigmentosum group G: implications for a second XPG function. Proc Natl Acad Sci USA. 94:3116-21. 4. Caonstaintinou, A. et al. (1999) Conserved residues of human XPG protein important for nuclease activity and function in nucleotide excision repair. J Biol Chem.274:5637-48. 5. Araujo, S. J., Nigg, E. A. and Wood, R. D. (2001) Strong functional interactions of TFIIH with XPC and XPG in human DNA nucleotide excision repair, without a preassembled repairosome. Mol Cell Biol. 21:2281-91. |
| Additional info: | Recognizes the Xenoderma Pigmentation protein G. |
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