ZBP-89 (E84) Peptide

Cat no: BS2510P

Supplier: Bioworld Technology, Inc.

0 reviews | Write a Review Pencil

Description
Additional Information

ZBP-89, also known as BFCOL1, BERF1 and ZNF 148, is a zinc finger transcription factor that is universally expressed. ZBP-89, a Kruppel-like repressor protein, is the silencer element binding factor for Vimentin. ZBP-89 has been shown to bind to GC-rich DNA elements in promoters for gastrin, ornithine decarboxylase and the cyclin-dependent kinase inhibitor p21 (also designated Cip1 or WAF1). ZBP-89 expression is induced by trans-retinoic acid or butyrate, which also induces terminal differentiation of colon cancer cells. ZBP-89 cooperates with histone acetyltransferase coactivator p300 in the regulation of p21, a cyclin-dependent kinase inhibitor whose associated gene is a target gene of p53. ZBP-89 also regulates cell proliferation, in part, through its ability to directly bind the p53 protein and retard its nuclear export. Elevated levels of ZBP-89 induce growth arrest and apoptosis in human gastrointestinal cells.

Catalogue number:	BS2510P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	Q9UQR1
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide ZBP-89 (E84). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	ZNF148; Zinc finger protein 148
Additional info:	This peptide can be used with studies using BS2510 ZBP-89 (E84) pAb.

See Full Product Listings >

ZBP-89 (E84) Peptide

Cat no: BS2510P

Get Quote

About Biosave

Product Categories

Information


Get a Quote Direct from Bioworld Technology, Inc.




By submitting this form you agree to your details being passed to Bioworld Technology, Inc. for the purpose of generating the best quote*