ZIP-kinase (K261) Peptide

Cat no: BS3724P

Supplier: Bioworld Technology, Inc.

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Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certainserine/threonine protein kinases, such as ASK1 and RIP, are mediators of apoptosis. A novel serine/threonine kinase that mediates apoptosis was recently identified and designated ZIP kinase. ZIP kinase contains an N terminal kinase domain and a C terminal leucine zipper structure and binds to ATF4 that is a member of ATF/CREBfamily. ZIP kinase has high sequence homology to DAP kinase (death associated protein kinase), which is a mediator of apoptosis induced by gamma interferon. Overexpression of ZIP kinase induces apoptosis. ZIP and DAP kinases represent a novel kinase family, which mediates apoptosis through their catalytic activities. The messenger RNA was ubiquitously expressed in various tissues.

Catalogue number:	BS3724P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	O43293
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide ZIP-kinase (K261). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	ZIPK; ZIP kinase; ZIP; FLJ36473; EC 2.7.11.1; Dlk; Death associated protein kinase 3; Death associated kinase 3; Dapk3; Dapk 3; DAP like kinase; DAP kinase 3
Additional info:	This peptide can be used with studies using BS3724 ZIP-kinase (K261) pAb.

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ZIP-kinase (K261) Peptide

Cat no: BS3724P

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