Home  >  Products  >  ZNF638 pAb
ZNF638 pAb

ZNF638 pAb

Cat no: BS5827

Supplier: Bioworld Technology, Inc.
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. NP220 (Nuclear protein 220), also designated Zinc finger protein 638 (ZNF638) or Cutaneous T-cell lymphoma-associated antigen se33-1, is a 1978 amino acid protein that contains one matrin-type zinc finger and two RRM (RNA recognition motif) domains, suggesting a role in transcriptional regulation. NP220 binds to double-stranded DNA fragments by recognizing clusters of cytidines. NP220 interacts with FHL-2 and is also thought to be phosphorylated by ATM or ATR upon DNA damage. It exists as five isoforms as a result of alternative splicing events. Isoform five of NP220 is a tumor-associated antigen found in several cutaneous T-cell lymphoma (CTCL), and in particular in mycosis fungoides patients and in Sezary syndrome patients.
Catalogue number: BS5827
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: Q14966
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 1308-1353 of Human ZNF638.
Species: ZNF638 pAb detects endogenous levels of ZNF638 protein.
Molecular weight: ~ 220 kDa,120 kDa (Isoform 5)
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Zinc finger protein 638; Cutaneous T-cell lymphoma-associated antigen se33-1; CTCL-associated antigen se33-1; Nuclear protein 220; Zinc finger matrin-like protein; NP220; ZFML
Additional info: For research use only, not for use in diagnostic procedure.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
Bioworld Technology, Inc.
Get a Quote Direct from
Bioworld Technology, Inc.

By submitting this form you agree to your details being passed to Bioworld Technology, Inc. for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave