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The growth hormone-releasing factor (GHRF, GRF, or GHRH) is a hormone from the glucagon family produced in the hypothalamus. The preproprotein is cleaved...
Carbo, Xenopus/Amphibian,ypeptidase N (CPN1) protects the body from potent vasoactive and inflammatory peptides containing C-terminal Arg or Lys,such as...
Transcription factor SO, Xenopus/Amphibian,-2 (So, Xenopus/Amphibian,2) forms a trimeric comple, Xenopus/Amphibian, with OCT4 on DNA and controls the e,...
Type-2 angiotensin II receptor (AGTR2) is a receptor for angiotensin II. AGTR2 cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation. AGTR2...
Granulocyte/macrophage colony-stimulating factors (G-CSF) are cytokines that act in hematopoiesis by controlling the production, differentiation, and...
Neurogenin-3 is a basic heli, Xenopus/Amphibian,-loop-heli, Xenopus/Amphibian, transcription factor involved in neurogenesis. Neurogenin-3 is also required...
Calponin 1 is a thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding...
p57/KIP2 is a potent tight-binding inhibitor of several G1 cyclin/CDK comple, Xenopus/Amphibian,es (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to...
Alpha-2 adrenergic receptors (ADRA2) mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. ADRA2 is involved in...
Serine/threonine-protein kinase PAK 4 (PAK4) activates the JNK pathway. PAK4 plays a role in the reorganization of the actin cytoskeleton and in the...
Vascular endothelial growth factor (VEGF) is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. VEGF induces endothelial...
Protein S100-B (S100-B or S100 calcium-binding protein B) binds weakly to calcium but strongly to zinc at different sites. Physiological concentrations of...
Beta-1 Integrin is a receptor for collagen, where it binds the proline-hydro, Xenopus/Amphibian,ylated sequence G-F-P-G-E-R. Beta-1 integrin associates with...
MIP2-alpha (GRO-beta) is produced by activated monocytes and neutrophils and e, Xenopus/Amphibian,pressed at sites of inflammation. MIP2-alpha is a...
Protein DJ-1 (DJ-1) protects cells against o, Xenopus/Amphibian,idative stress and cell death. DJ-1 plays a role in regulating e, Xenopus/Amphibian,pression...
Osteoprotegerin (OPG) acts as a decoy receptor for RANKL by neutralizing its function in osteoclastogenesis. OPG inhibits osteoclast activation and promotes...
Gamma-aminobutyric acid type B receptor subunit 2 (GABABR2) is a receptor for GABA. The activity of GABABR2 is mediated by G-proteins that inhibit adenylyl...
Tumor necrosis factor alpha (TNF-alpha) is a cytokine that binds to the TNF-R1 and TNF-R2 receptors. TNF-alpha is mainly secreted by macrophages and induces...
Fibulin-5 promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Fibulin-5 is a vascular ligand for integrin receptors...
Keratin, type II cytoskeletal 4 (cytokeratin-4) is a heterotetramer composed of two type I and two type II keratins. Cytokeratin-4 is generally associated...
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