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Simvastatin is a slightly more hydrophobic semi-synthetic analog of lovastatin. Like lovastatin, simvastatin is a specific inhibitor of HMG-CoA reductase and...
Antibiotic Sch 725674 is a macrocyclic lactone structurally related to gloeosporone, a self-germination inhibitor produced by Colletotrichum gloeosporioides....
Sch 38519 is an isochromanequinone, structurally related to lactoquinomycin. Sch 38519 inhibits thrombin-induced aggregation of human platelets and is active...
Salinomycin is a polyether ionophore with broad spectrum Gram +ve and anti-coccidial activity. Salinomycin has a high affinity for monovalent cations,...
Pneumocandin B0 is the major analogue of a family of lipopeptides isolated from several species of several different genera, notably Cryptosporiopsis, Glarea...
Platensimycin is a novel broad spectrum Gram-positive antibiotic produced by strains of Streptomyces platensis. Its discovery was heralded by high profile...
Platencin is a more potent analogue of Platensimycin also discovered from a strain of Streptomyces platensis. Platencin shows potent in vivo efficacy without...
Phenelfamycin E is the major analogue of the phenelfamycin complex produced by several species of Strepyomyces. The phenelfamycins are potent antibiotics...
Pentostatin is a potent antitumor antibiotic isolated from a Streptomyces species. Pentostatin is a potent inhibitor of adenine deaminase and has been used...
Penitrem A is a tremorgenic mycotoxin isolated from Penicillium species. Penitrem A acts as a selective blocker of high- conductance Ca2+-activated potassium...
Paxilline is a tremorgenic mycotoxin isolated from species of Penicillium, Acremonium and Emericella. Paxilline acts as a selective blocker of...
Novobiocin is an aminocoumarin antibiotic isolated from a number of species of Streptomyces. Novobiocin exhibits broad spectrum Gram +ve activity and was...
Nonactin is the smallest member of the macrotetrolide complex produced by a range of Streptomyces species. Originally the name, nonactin, reflected the lack...
Moniliformin is a potent, water-soluble mycotoxin produced by several species of Fusarium. Comparative studies of the toxicity of moniliformin to chicken...
Monensin A is a polyether antibiotic first isolated from Streptomyces cinnamonensis in 1967. Monensin is a broad- spectrum anticoccicidial antibiotic also...
Moxidectin is a semi-synthetic milbemycin derived from nemadectin by selective oxidation followed by methyloximation. Moxidectin was patented in 1991 as an...
Moenomycin complex is a mixture of five major components: A, A12, C1, C3 and C4 isolated from several strains of Streptomyces in the 1960s. Moenomycins are...
Milbemycin oxime is a semi-synthetic macrocyclic lactone prepared by the oxidation and oximation of a mixture of two natural products, milbemycin A3 and A4...
Mithramycin was the first of the aureolic acid class of antitumor antibiotics isolated from Streptomyces. Mithramycin inhibits transcription and protein...
Lasalocid is a polyether ionophore with potent antibacterial activity. Lasalocid was developed as an animal health product for treatment of coccidia....
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