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United States Biological

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NOXA (Phorbol-12-myristate-13-acetate-induced Protein 1, PMA-induced Protein 1, Immediate-early-response Protein APR, Protein Noxa, PMAIP1)
NOXA (Phorbol-12-myristate-13-acetate-induced Protein 1, PMA-induced Protein 1, Immediate-early-response Protein APR, Protein Noxa, PMAIP1)
United States Biological

Noxa is a BH3-only member of the Bcl-2 family. Expression of Noxa gene involves direct activation of its promotor by p53. Increased expression of Noxa...

Notch1 (Neurogenic Locus Notch Homolog Protein 1, Notch 1, Motch A, mT14, p300, Motch)
Notch1 (Neurogenic Locus Notch Homolog Protein 1, Notch 1, Motch A, mT14, p300, Motch)
United States Biological

Notch proteins are transmembrane receptor that regluate cell fate decisions. Four Notch homologs have been identified in mammals namely Notch 1, Notch 2,...

NIK (Mitogen-activated Protein Kinase Kinase Kinase 14, NF-kappa-beta-inducing Kinase, HsNIK, Serine/Threonine-protein Kinase NIK, MAP3K14)
NIK (Mitogen-activated Protein Kinase Kinase Kinase 14, NF-kappa-beta-inducing Kinase, HsNIK, Serine/Threonine-protein Kinase NIK, MAP3K14)
United States Biological

NIK (NF-kB-inducing kinase) is a member of the MAP kinase kinase kinase family that binds TRAF2 and stimulates NF-kB activity. NIK was initially isolated...

Nfkbia (NF-kappa-B Inhibitor alpha, I-kappa-B-alpha, IkB-alpha, IkappaBalpha, Ikba)
Nfkbia (NF-kappa-B Inhibitor alpha, I-kappa-B-alpha, IkB-alpha, IkappaBalpha, Ikba)
United States Biological

IkB-alpha protein is a NF-kB inhibitory protein. It binds NF-kB and retains the complex in the cytoplasm, thereby preventing it from entering into nucleus...

NFkB p65 (Transcription Factor p65, Nuclear Factor NF-kappa-B p65 Subunit, Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-cells 3, Rela, Nfkb3)
NFkB p65 (Transcription Factor p65, Nuclear Factor NF-kappa-B p65 Subunit, Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-cells 3, Rela, Nfkb3)
United States Biological

NFkB is a heterodimer that consists of a 50kD DNA binding subunit (p50) and a 65kD transactivation subunit (p65/RelA). Both of these subunits exhibit...

NFkB p65 (Transcription Factor p65, Nuclear Factor NF-kappa-B p65 Subunit, Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-cells 3, RELA, NFKB3)
NFkB p65 (Transcription Factor p65, Nuclear Factor NF-kappa-B p65 Subunit, Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-cells 3, RELA, NFKB3)
United States Biological

NFkB was identified as a sequence specific transcriptional activator that binds to the intronic enhancer of kappa light chain gene in B lymphocytes. NFkB is...

Neurexin (NRXN)
Neurexin (NRXN)
United States Biological

Neurexins comprise a family of neuronal cell surface proteins present primarily in the brain. Neurexins are thought to serve as signaling receptors and may...

Nestin (NES, Nbla00170)
Nestin (NES, Nbla00170)
United States Biological

Nestin is a type IV intermediate filament protein expressed by neuroepithelial stem cells and which has been proposed to represent a marker for putative...

Nestin (NES, Nbla00170)
Nestin (NES, Nbla00170)
United States Biological

Nestin may play a role in the trafficking and distribution of IF proteins and potentially other cellular factors to daughter cells during progenitor cell...

Nectin 3 (Nectin-3, CD113, Poliovirus Receptor-related Protein 3, Pvrl3)
Nectin 3 (Nectin-3, CD113, Poliovirus Receptor-related Protein 3, Pvrl3)
United States Biological

Nectin is a cell-adhesion molecule that belongs to the immunoglobilin superfamily and is also known as the poliovirus receptor-related protein or PPR. Nectin...

NAIP (Baculoviral IAP Repeat-containing Protein 1, Neuronal Apoptosis Inhibitory Protein, BIRC1)
NAIP (Baculoviral IAP Repeat-containing Protein 1, Neuronal Apoptosis Inhibitory Protein, BIRC1)
United States Biological

NAIP (neuronal apoptosis inhibitor protein) is a member of the IAPs (inhibitor of apoptosis proteins) that function in cell death pathways to inhibit...

Naa35 (N-alpha-acetyltransferase 35, NatC Auxiliary Subunit, Corneal Wound-healing-related Protein, Embryonic Growth-associated Protein, Protein MAK10 Homolog, Egap, Emb8, Mak10)
Naa35 (N-alpha-acetyltransferase 35, NatC Auxiliary Subunit, Corneal Wound-healing-related Protein, Embryonic Growth-associated Protein, Protein MAK10 Homolog, Egap, Emb8, Mak10)
United States Biological

MAK10 protein regulates the proliferation of smooth muscle cells. The mammalian homolog of yeast MAK10, also known as EGAP, is one subunit of a novel...

MYST2 (Histone Acetyltransferase KAT7, Histone Acetyltransferase Binding to ORC1, Lysine Acetyltransferase 7, MOZ, YBF2/SAS3, SAS2 and TIP60 Protein 2, MYST-2, KAT7, HBO1, HBOa)
MYST2 (Histone Acetyltransferase KAT7, Histone Acetyltransferase Binding to ORC1, Lysine Acetyltransferase 7, MOZ, YBF2/SAS3, SAS2 and TIP60 Protein 2, MYST-2, KAT7, HBO1, HBOa)
United States Biological

Histone acetyltransferases (HATs) have been implicated in a number of cellular functions including gene regulation, DNA synthesis, and repair. Histone...

Myeloperoxidase (MPO, pANCA)
Myeloperoxidase (MPO, pANCA)
United States Biological

Myeloperoxidase (MPO) is highly expressed in neutrophils and polymorphonuclear luekocytes. MPO is expressed as a dimer in regular neutrophils with a 140kD....

MyD88 (Myeloid Differentiation Primary Response Protein MyD88)
MyD88 (Myeloid Differentiation Primary Response Protein MyD88)
United States Biological

MyD88 was identified as an adapter molecule in the IL-1 signaling pathway. MyD88 associates with and recruits IRAK to the IL-1 receptor complex in response...

MYD88 (Myeloid Differentiation Primary Response Protein MyD88)
MYD88 (Myeloid Differentiation Primary Response Protein MyD88)
United States Biological

MyD88 was identified as an adapter molecule in the IL-1 signaling pathway. MyD88 associates with and recruits IRAK to the IL-1 receptor complex in response...

MTA2 (Metastasis-associated Protein MTA2, Metastasis-associated 1-like 1, MTA1-L1 Protein, p53 Target Protein in Deacetylase Complex, MTA1L1, PID)
MTA2 (Metastasis-associated Protein MTA2, Metastasis-associated 1-like 1, MTA1-L1 Protein, p53 Target Protein in Deacetylase Complex, MTA1L1, PID)
United States Biological

PID/MTA2, also termed MTA1-L1, is a novel molecule that has been found to be involved in p53 pathway. PID/MTA2 modulates the enzymatic activity of the...

Mst2 (Mammalian STE20-like Protein Kinase 2, MST-2, FLJ90748, KRS1, Serine/threonine Protein Kinase 3, STK3, Serine/threonine Protein Kinase Krs1, STE20-like Kinase MST2)
Mst2 (Mammalian STE20-like Protein Kinase 2, MST-2, FLJ90748, KRS1, Serine/threonine Protein Kinase 3, STK3, Serine/threonine Protein Kinase Krs1, STE20-like Kinase MST2)
United States Biological

Krs-1 protein exhibits stress-induced activity in response to staurosporine and okadaic acid. When the kinase-inactive mutant form of MST/Krs protein was...

MSH2 (DNA Mismatch Repair Protein Msh2, hMSH2, MutS Protein Homolog 2)
MSH2 (DNA Mismatch Repair Protein Msh2, hMSH2, MutS Protein Homolog 2)
United States Biological

DNA mismatch repair genes have been found to be associated with hereditary nonpolyposis colorectal cancer (HNPCC). Inherited mutations in the MSH2 were...

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