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Protein names: Probable ribonuclease 11, Short name=RNase 11. Gene names: RNASE11, C14orf6. ORF Names: UNQ5832/PRO19669. Subcellular location:Secreted....
Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein...
HSP 90 family members guide the normal folding, intracellular disposition and proteolytic turnover of many key regulators of cell growth, differentiation and...
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro, in the presence or in the absence of BRCA1-BARD1 E3...
?Mammals defend themselves against intracellular pathogens through presentation of cytoplasmically-derived short pathogenic peptides to the cell surface of...
The inactive ternary complex of cyclin D/CDK4 and p27 Kip1 requires extracellular mitogenic stimuli for the release and degradation of p27 concomitant with a...
Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in...
Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A...
FAM3B (family with sequence similarity 3, member B), also known as ORF9, C21orf11 or PANDER, is a 235 amino acid secreted protein that localizes to discrete...
Target-derived survival factor for peripheral sensory sympathetic neurons.Defects in NTF4 may be associated with susceptibility to primary open angle...
Alkaline phosphatases (AP) are glycosyl-phosphatidylinositol (GPI)-anchored, dimeric, Zn2+ metallated glycoproteins that catalyze the hydrolysis of...
TBRG4 (transforming growth factor beta regulator 4), also known as CPR2 (cell cycle progression restoration protein 2) or FAST 4 (FAST kinase...
Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is...
Cullin proteins comprise a distinct family of mediators that participate in the selective targeting of proteins for ubiquitin (Ub)-mediated proteolysis....
Required for autophagy. Conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate...
Acyl-CoA synthetase probably involved in bile acid metabolism. Proposed to activate C27 precurors of bile acids to their CoA thioesters derivatives before...
Plays an essential role in the mitochondrial beta-oxidation of short chain fatty acids. Exerts it highest activity toward 3-hydroxybutyryl-CoA. Defects in...
Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by...
Ribonucleases are ubiquitous enzymes involved in RNA metabolism and are classified in several families on the basis of their structural, catalytic and...
?Cysteine-rich proteins (CRPs) participate in the organization of multiprotein complexes, both in the cytoplasm, where they participate in cytoskeletal...
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