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The type II cAMP-protein kinase (PKA) is a multifunctional kinase with a broad range of substrates. Specificity of PKA signaling is thought to be mediated by...
ADH7 (alcohol dehydrogenase 7 (class IV), micro or o polypeptide), is a 386 amino acid protein belonging to the zinc-containing alcohol dehydrogenase family...
Adenosine is involved in a variety of processes, including the synthesis of urea, the anti-inflammatory response and the inhibition of protein synthesis. The...
ABCG1 (also designated ABC8 or human white gene), a member of the evolutionary conserved family of ATP-binding cassette (ABC) transporters, exhibits high...
The peroxisomal membrane contains several ATP-binding cassette (ABC) transporters, ABCD1-4 that are known to be present in the human peroxisome membrane. All...
The peroxisomal membrane contains several ATP-binding cassette (ABC) transporters, ABCD1-4 that are known to be present in the human peroxisome membrane. All...
SERPINA1 is secreted and is a serine protease inhibitor which its targets include elastase, plasmin, collagenase, thrombin, leucocytic proteases, trypsin,...
A20, also referred to as TNF-(alpha)-induced protein 3 (TNFAIP3), is cytokine-inducible protein that functions to inhibit apoptosis and activate NF-kB. It...
A1BG ((alpha)-1B-glycoprotein), also known as A1B, ABG, GAB or HYST2477, is a 495 amino acid secreted glycoprotein that contains five immunoglobulin...
Adenylyl cyclases function to convert ATP to cyclic AMP in response to activation by a variety of hormones, neurotransmitters and other regulatory molecules....
The 4.1 gene family encodes a group of multifunctional cytoskeletal proteins (4.1R, 4.1G, 4.1N and 4.1B), which are predominantly expressed in the nervous...
Glucocorticoid hormone action in target tissues is modulated by 11b-hydroxysteroid dehydrogenase (11b-HSD), which catalyzes the interconversion of hormonally...
LKB1, a member of the serine/threonine kinase family, is a tumor suppressor. Physically associates with p53, it regulates specific p53 dependent apoptosis...
LKB1, a member of the serine/threonine kinase family, is a tumor suppressor. Physically associates with p53, it regulates specific p53 dependent apoptosis...
Stat 5a protein is a transcription factor activated by hormone and cytokines. Two highly related, but distinct Stat 5 genes (Stat 5a and Stat 5b) were...
Signal transducer and activator of transcription that mediates signaling by interferons (IFNs). Following type I IFN (IFN-alpha and IFN-beta) binding to cell...
The major translational products of each of the eight members of the Src gene family identified to date are membrane-associated tyrosine protein kinases that...
Several serine/threonine protein kinases have been implicated as intermediates in signal transduction pathways. These include ERK/MAP kinases, ribosomal S6...
Activation of PKC is one of the earliest events in a cascade leading to a variety of cellular responses such as secretion, gene expression, proliferation and...
Activation of PKC is one of the earliest events in a cascade leading to a variety of cellular responses such as secretion, gene expression, proliferation and...
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