3-Methyl Adenine

Cat no: 016471

Supplier: United States Biological

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3-MA inhibits autophagy by blocking autophagosome formation via the inhibition of type III Phosphatidylinositol 3-kinases (PI-3K). For use as an autophagy inhibitor, 3-MA is typically used at a concentration of 5 mM. Melting Point: As Reported Solubility: As Reported Method for Determining Identity: Proton NMR (DMSO-d6, CD3OD) Spectroscopic and Mass Spectrometric Analysis TLC Conditions: As Reported Water Content: As Reported Elemental Analysis: Calculated: %C: 48.32, %H: 4.73, %N: 46.95 Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at 4 degrees C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards:

Catalogue number:	016471
Size:	100mg
Form:	As Reported
Purity:	~90%
Alternative names:	3-Methyl-3H-purin-6-amine; 3-Methyl-6-aminopurine; 3-Methyladenine; 6-Amino-3-methylpurine; N3-Methyladenine; NSC 66389;
References:	Munafo, D., et al.: J. Cell Sci., 114, 3619 (2001), Aggarwal, B., et al.: Biochem. Pharmacol., 71, 1397 (2006), Hayat, M., et al.: Oncologist, 12, 20 (2007), Prasad, S., et al.: J. Biol. Chem., 286, 5546 (2010),

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3-Methyl Adenine

Cat no: 016471

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