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Caspase 2 (CASP2, CASP-2, ICH1, Protease ICH-1, Neural Precursor Cell Expressed Developmentally Down-regulated 2, NEDD2, NEDD-2)

Caspase 2 (CASP2, CASP-2, ICH1, Protease ICH-1, Neural Precursor Cell Expressed Developmentally Down-regulated 2, NEDD2, NEDD-2)

Cat no: C2086-72

Supplier: United States Biological
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Caspase 2 is a member of the cysteine-aspartic acid protease (caspase) family and acts as both a positive and negative regulator of apoptosis. Overexpression of the full length Caspase 2 (Isoform ICH-1L) in some cell types results in apoptosis whereas the overexpression of an alternative Caspase 2 (ICH-1S) splice variant suppresses apoptosis. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 0.5-1ug/ml Immunohistochemistry (Paraffin and Formalin): 1-2.0ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C2086-72
Reactivities: Human, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug
Form: Supplied as a lyophilized powder from PBS, 5% BSA, 0.05% thimerosal, 0.05% sodium azide. Reconstitute with 100ul of sterile dH20.
P type: Pab
Purity: Purified by affinity chromatography.
Alternative names: Caspase-2 Apoptosis-related Cysteine Peptidase, Apoptosis-related Cysteine Peptidase, EC=3.4.22.55
Additional info: Recognizes human Caspase 2. Species Crossreactivity: rat.

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