Home  >  Products  >  Caspase 3 (caspase 3, apoptosis-related cysteine peptidase, apopain,CASP-3, Caspase-3, CPP32, CPP-32, CPP32B, Cysteine Protease CPP32, SCA-1, SREBP cleavage activity 1, Yama, Yama Protein, CASP3)
Caspase 3 (caspase 3, apoptosis-related cysteine peptidase, apopain,CASP-3, Caspase-3, CPP32, CPP-32, CPP32B, Cysteine Protease CPP32, SCA-1, SREBP cleavage activity 1, Yama, Yama Protein, CASP3)

Caspase 3 (caspase 3, apoptosis-related cysteine peptidase, apopain,CASP-3, Caspase-3, CPP32, CPP-32, CPP32B, Cysteine Protease CPP32, SCA-1, SREBP cleavage activity 1, Yama, Yama Protein, CASP3)

Cat no: C2087-01A

Supplier: United States Biological
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Caspase-3 (CPP32, Apopain) is the most extensively studied apoptotic protein. Caspase-3 is synthesized as an inactive proenzyme (32kD) that is processed in cells undergoing apoptosis by self-proteolysis and/or cleavage by another upstream protease. The processed form of caspase-3 consists of large (17kD) and small (12kD) subunits which associate to form an active enzyme. The active caspase-3 proteolytically cleaves and activates other caspases, as well as relevant targets in the cells such as PARP and DFF. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot:1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C2087-01A
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug
Form: Supplied as a lyophilized powder from PBS, pH 7.4, 5% BSA, 0.05% thimerosal, 0.05% sodium azide. Reconstitute with sterile dH2O.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes human Caspase 3. Species Cross-Reactivity: mouse, rat.

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